ParkinsonFranceV1, Main, Exploration, bibRecord, 000373

A combined pharmacokinetic/pharmacodynamic model of levodopa motor response and dyskinesia in Parkinson's disease patients.

Identifieur interne : 000373 ( Main/Exploration ); précédent : 000372; suivant : 000374

A combined pharmacokinetic/pharmacodynamic model of levodopa motor response and dyskinesia in Parkinson's disease patients.

Auteurs : N. Simon [France] ; F. Viallet [France] ; A. Boulamery [France] ; A. Eusebio [France] ; D. Gayraud [France] ; J-P Azulay [France]

Source :

European journal of clinical pharmacology [ 1432-1041 ] ; 2016.

RBID : pubmed:26936272

English descriptors

KwdEn :
- Aged, Antiparkinson Agents (adverse effects), Antiparkinson Agents (therapeutic use), Dyskinesia, Drug-Induced (etiology), Female, Humans, Levodopa (adverse effects), Levodopa (therapeutic use), Male, Middle Aged, Models, Biological, Parkinson Disease (drug therapy), Prospective Studies.
MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesia, Drug-Induced.
- Aged, Female, Humans, Male, Middle Aged, Models, Biological, Prospective Studies.

Abstract

Levodopa is the reference treatment for Parkinson's disease. However, after several years of treatment, dyskinesia may occur and strategies to overcome this side effect still need to be explored. We identified a unique population pharmacokinetic/pharmacodynamic model in Parkinson's disease to investigate the relationship and dissociability of motor response and dyskinesia.

DOI: 10.1007/s00228-016-2034-0
PubMed: 26936272

Affiliations:

Le document en format XML

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La maladie de Parkinson en France (serveur d'exploration)

A combined pharmacokinetic/pharmacodynamic model of levodopa motor response and dyskinesia in Parkinson's disease patients.

A combined pharmacokinetic/pharmacodynamic model of levodopa motor response and dyskinesia in Parkinson's disease patients.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson en France (serveur d'exploration)
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